2009, discovery of a new phenotype for micro organism in slender nanofluidic slits; and to start with detection of local protein structures along DNA using strong-state nanopores

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We develop point-of-treatment diagnostics take a look at of neglected tropical conditions inside of resource-confined options, depending on Crspr/Cas9 detecting of pathogen’s DNA in physique fluids.

SMC complexes can pass Actual physical roadblocks larger than their ring dimensions, indicating a nontopological mechanism for DNA loop extrusion

A lot of relevant developments adopted, the place our team recognized unique transistor variants for instance one-electron transistors at room temperature and intramolecular nanotube junctions that acted as rectifying diodes, and coupled multiple transistors into small evidence-of-basic principle Digital circuits.

2011, 1st in vitro measurements of transport throughout only one biomimetic nuclear pore elaborate; enhancement of multiplexed magnetic tweezers for kilo-molecule experiments; and solved the system of homology recognition in DNA homologous recombination

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Quite neat, but that wasn’t actually where https://www.ceesdekker.net by my interest lay. I wished to pioneer And that i experienced the feeling that was no more probable, because the most exciting fundamental insights had previously been uncovered. But my industry had produced quite a few exciting new resources to measure particular person molecules. I made a decision which i desired to use this to biology, to take a look at it from the Actual physical standpoint.’

Testing pseudotopological and nontopological designs for SMC-driven DNA loop extrusion from roadblock-traversal experiments

Character Physics many thanks the anonymous reviewers for his or her contribution to your peer assessment of the operate.

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Dekker heeft fundamentele ontdekkingen gedaan op het gebied van koolstof nanobuisjes. Mede vanwege deze werkzaamheden is hij al jaren de meest geciteerde fysicus in Nederland. Tegenwoordig onderzoekt hij achieved enkel-molecuultechnieken de biofysica van moleculen in de biologische cel. Dekker is naast zijn wetenschappelijk werk ook bekend vanwege zijn belangstelling voor de relatie tussen geloof en wetenschap en de discussie rond intelligent layout in 2005. (nl)